Compound Library Synthesis
High-throughput Chemical Synthesis Powered by Automation
- We provide the tools and expertise you need to accelerate your project.
FOCUS ON YOUR SCIENCE. XtalPi will handle the rest.
Synthetic
Route Design
400+ experienced synthetic chemists
AI-assisted/human synthetic route design
Wide coverage of chemical space
Automated
Discovery Chemistry
30000 ft² automated synthesis laboratory
200+ autonomous chemical synthesis workstations
Covering 80% of commonly used organic chemistry reactions
Analysis and
Purification
LCMS/Prep-HPLC/NMR/other analytical instruments as required
High-throughput work-up and purification (>250 compounds per day)
trict QA/QC
Compound
Management
Secure, flexible, and trackable compound management
Flexible cherry picking, reformatting and shipping
LCMS and/or NMR quality inspection before shipping
- Human-machine collaboration offers efficient, reliable, and safe chemical synthesis.
Efficient24/7 autonomous high-throughput reaction set-up and monitoring
One workstation can simultaneously perform 200 reactions
ReliableReproducibility delivered through automation
Generation of clean, machine readable reaction data
Reduction in human error
SafeAutomated reaction set-up and monitoring
No chemical exposure to human chemist
- Case Study
Project ScopeSynthesize and purify 400 molecules through single-step library reactions in 4 weeks or less.
Solution Provided by XtalPiUtilized a human-machine“co-botic” model consisting of : 1 chemist + 1 lab technician + automated chemical synthesis workstations.
Experimental ResultsAfter the design of the experiments was completed by the chemist, a total of 600 library reactions were set-up utilizing the automated workstations in collaboration with the human technician.
Post analysis and purification, the co-botic team delivered a total of 392 compounds in only 9 days.
XtalPi is keenly aware that every research partner has unique needs and priorities, and is happy to create a customized solution to optimize your research program
